Deep sensory-vascular profiling of Fabry patients

niversitätsklinikum Schleswig-Holstein, Campus Kiel0 个研究点目标入组 50 人开始时间: 2023年8月8日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Fabry patients
•- patients suffering from chronic pain
•- on a stable therapy regimen for at least two years or not receiving treatment
•- able to give informed consent
•healthy controls
•Chosen according to the criteria provided in: Gierthmühlen J, Enax-Krumova EK, Attal N, Bouhassira D, Cruccu G, Finnerup NB, Haanpää M, Hansson P, Jensen TS, Freynhagen R, Kennedy JD, Mainka T, Rice ASC, Segerdahl M, Sindrup SH, Serra J, Tölle T, Treede RD, Baron R, Maier C. Who is healthy? Aspects to consider when including healthy volunteers in QST--based studies-a consensus statement by the EUROPAIN and NEUROPAIN consortia. Pain. 2015 Nov;156(11):2203-2211. doi: 10.1097/j.pain.0000000000000227. PMID: 26075963.

•Fabry patients:
•- severe depression
•- chronic alcoholism (regular consumption of alcohol exceeding 10 g a day for women and 20 g a day for men) or substance abuse (including consumption of any illegal drugs, consumption of prescription medication (e.g. opioids, benzodiazepines) either not prescribed to the patients or in overly high doses)
•- The use of medical cannabis as well as CBD or THC preparation or supplement-grade CBD (according to German regulations) is permitted. Patients consuming cannabis which is not prescribed by a medical professional and obtained from a pharmacy or licensed dispensary will be excluded.
•- patients on investigational drugs
•- any reason preventing an accurate understanding of the tests

发起方

niversitätsklinikum Schleswig-Holstein, Campus Kiel