Sickle Cell Anemia Screening and Prevention in Northern Israel

Completed

• Conditions: Thalassemia; Sickle Cell Anemia
• Interventions: Other: Observational

• Registration Number: NCT00735488
• Lead Sponsor: HaEmek Medical Center, Israel

Brief Summary

Since 1987, a screening for β Thalassemia in pregnant women is carried on in northern Israel, and from 1999 all the samples were tested also for Hgb S, Hgb C, Hgb D, Hgb O Arab and others.

In this study, the investigators intend to summarize the results of this preventive program aiming to detect couples at risk for having offspring with Thalassemia or SCA, the compliance regard to genetic counseling and prenatal diagnosis and the incidence of new affected babies born.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05
• Study First Submitted: 2008-08-14
• Study First Submitted QC: 2008-08-14
• Study First Posted: 2008-08-15
• Primary Completion: 2009-03
• Study Completion: 2009-03
• Status Verified: 2015-08
• Last Update Submitted: 2015-08-30
• Last Update Posted: 2015-09-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

All pregnant women tested and their husband in those cases that the woman test revealed abnormal hemoglobin.

Exclusion Criteria

No exclusion criteria.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
A	Observational	Thalassemia Minor carriers
B	Observational	Sickle cell carriers

Primary Outcome Measures

Name	Time	Method
Number of carriers detected	End of study

Secondary Outcome Measures

Name	Time	Method
Couples referred for prenatal diagnosis	End of study

Trial Locations

Locations (1)

Pediatric Hematology Unit - Ha'Emek Medical Center; 🇮🇱 Afula, Israel