Influence of vibrationand sensorimotor training on CIPN of the upper extremity - pilot study

Not Applicable

Recruiting

• Conditions: G62; Other polyneuropathies

• Registration Number: DRKS00023287
• Lead Sponsor: niklinik Köln - CIO

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• under acute medical therapy (chemotherapy, immunotherapy) and abnormal sensations, as well as pain in the hands (numbness, tingling, burning)
• in the case of an upcoming chemotherapy with the following active substances: taxanes, vinca alkaloids, platinum derivatives or in the case of an upcoming immunotherapy with the following active substances: checkpoint inhibitors, antibodies
• if a polyneuropathy of another origin (e.g. diabetes mellitus) that already existed can be ruled out

Exclusion Criteria

• Polyneuropathy of another origin that already existed (e.g. due to diabetes mellitus; drug-toxic)
• For sensorimotor training: acute injury to the upper extremities which the intended training does not allow
• For vibration training (see also (Streckmann et al., 2014a)): Osteolysis, osteosynthesis, fracture of the upper extremities or metal removal in the last year (prerequisite for bone consolidation in the X-ray), acute thrombosis, shoulder TEP, cervical disc prosthesis
• Medical or mental health condition which, in the opinion of the investigator, does not allow the patient to take part in the study
• Unwillingness to save and pass on personal illness data within the scope of the protocol
• Participation in another sports study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of this study is to evaluate the effectiveness of vibration training and sensorimotor training with CIPN (chemotherapy and immunotherapy induced peripheral polyneuropathy) for the upper extremity.

Secondary Outcome Measures

Name	Time	Method
• Improvement of the quality of life and mental well-being (HADS)<br>• Improvement of the pain symptoms<br>• Which intervention group has the best effect on peripheral polyneuropathy?<br>• Development of a standard training therapy