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Lilly's Emotional and Physical Symptoms of Depression Study (LEAPS)

Phase 4
Completed
Conditions
Major Depressive Disorder
Registration Number
NCT00479726
Lead Sponsor
Eli Lilly and Company
Brief Summary

To assess the effectiveness of duloxetine administered once daily in patients with Major Depressive Disorder in a practice based setting

Detailed Description

To assess physical and emotional symptoms of depressed patients

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
8000
Inclusion Criteria

Not provided

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Exclusion Criteria
  • Are investigator site personnel directly affiliated with the study or immediate family
  • Are employed by Eli Lilly and Company
  • Have received treatment within the last 30 days or are currently enrolled in a study with a drug that has not received regulatory approval for any indication at time of study entry
  • Current substance dependence, excluding nicotine and caffeine
  • Treatment with a monoamine oxidase inhibitor within 14 days prior to visit 1 or potential need to use an MAOI within 5 days after discontinuation of study drug
  • Acute liver injury or severe (Child-Pugh Class C) cirrhosis
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Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Clinical Global Impression of Severity
Somatic Symptom Inventory
Depressive Symptomatology-Self Report
Secondary Outcome Measures
NameTimeMethod
Patient Global Impression of Improvement
Mood and Physical Symptoms in Depression
Quality of Life Enjoyment Satisfaction Questionnaire-Short form

Trial Locations

Locations (1)

For additional information regarding investigative sites for this trial,contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM - 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician

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Indianapolis, Indiana, United States

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