Iron Deficiency and Anemia in Cardiac Surgery

Completed

• Conditions: Cardiac Surgery; Anemia

• Registration Number: NCT04980911
• Lead Sponsor: Centre Hospitalier Régional Metz-Thionville

Brief Summary

Anemia and preoperative iron deficit in cardiac surgery are associated by an increased volume of transfusion and an increase in complications and/or mortality. Recent studies have shown that EPO and iron administration the days preceding the operation results in a reduction of perioperative transfusion for patients with preoperative anemia.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-04-12
• Study First Submitted: 2021-07-21
• Study First Submitted QC: 2021-07-21
• Study First Posted: 2021-07-28
• Primary Completion: 2022-03-18
• Study Completion: 2022-03-18
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-30
• Last Update Posted: 2022-08-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1711

Inclusion Criteria

• Patient with cardiac surgery
• With iron deficiency with or without anemia

Exclusion Criteria

• Anemia without iron deficiency
• Iron overload
• Jehovah's witnesses
• Endocarditis
• Treating neoplasia
• Uncontrolled hypertension
• With infection
• Alfa-epoetin hypersensitivity
• Hypersensitivity of hamster's protein
• Erythroblastopenia induced by erythropoietin
• Ferinject or mannitol allergy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of transfusion	Day 7	number of perioperative and post-operative transfusion

Secondary Outcome Measures

Name	Time	Method
Number of post operative complications	Day 7	Number of post-operative complications
Percentage of death	Day 7	Percentage of post-operative death

Trial Locations

Locations (1)

CHR Metz Thionville; 🇫🇷 Metz, Moselle, France