Improving Sensitivity of Urine Cytology for Bladder Cancer

Not Applicable

Withdrawn

• Conditions: Bladder Cancer
• Interventions: Device: La-Z-Boy Massage Chair Vibration Effect on Bladder Cancer Cell Concentration

• Registration Number: NCT01826097
• Lead Sponsor: Johns Hopkins University

Brief Summary

Can a commercially available vibrating chair increase the number of urothelial cells in a urine sample of healthy participants non-invasively? The investigators plan is participants will alternate 15 minutes of drinking eight fluid ounces of water and 15 minutes of sitting in the vibrating chair for one hour. The control group will alternate 15 minutes of drinking eight fluid ounces of water and 15 minutes of sitting in a non-vibrating chair for one hour. Then, urine samples will be collected and examined for urothelial cell concentration for both groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01
• Study First Submitted: 2013-04-01
• Study First Submitted QC: 2013-04-03
• Study First Posted: 2013-04-08
• Primary Completion: 2013-11
• Study Completion: 2013-11
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-30
• Last Update Posted: 2018-02-01

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

• Only adult male subjects who will not have surgery within a period of 2 weeks.
• Over the age of 18
• Have had a confirmed diagnosis of stage 0-4 transitional cell carcinoma within the last 30 days

Exclusion Criteria

• Cognitive impairment resulting in the inability to give informed consent
• Lack of spoken and written English resulting in the inability to give informed consent
• Presence of infectious disease
• Insulin dependent diabetes mellitus
• Endogenous osteosynthetical material implants
• Knee or hip prosthesis
• Pacemaker
• Epilepsy
• Musculo-skeletal disorders
• Weight in excess of 250 pounds
• Poor circulation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Vibration	La-Z-Boy Massage Chair Vibration Effect on Bladder Cancer Cell Concentration	Whole body vibration applied to a group of 20 bladder cancer patients.

Primary Outcome Measures

Name	Time	Method
Number of Cancer Cells	up to 24 weeks	Number of Cancer Cells in a 50 ml Urine

Trial Locations

Locations (1)

Johns Hopkins Hospital; 🇺🇸 Baltimore, Maryland, United States