The Study of EIT-guided Ventilation Strategy on ARDS Patients

Not Applicable

• Conditions: Pulmonary Perfusion; ARDS
• Interventions: Procedure: EIT-guided PEEP setting; Procedure: ARDS-net PEEP setting

• Registration Number: NCT04734340
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

This study is a clinical randomized controlled study.The objective of this study is to compare the prognosis of patients with ARDS between eit-v / q-oriented individualized ventilation strategy and traditional lung protection ventilation strategy, and to establish the demonstration application of eit-v / q-oriented ventilation strategy in ARDS

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-01
• Study Start: 2021-01-01
• Study First Submitted: 2021-01-28
• Study First Submitted QC: 2021-01-28
• Last Update Submitted: 2021-01-28
• Study First Posted: 2021-02-02
• Last Update Posted: 2021-02-02
• Primary Completion: 2023-06-01
• Study Completion: 2023-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. According to ARDS Berlin standard, ARDS, PaO2 / FiO2 < 200mmhg, peep > 5cmh2o;
2. According to clinical judgment, lung recruitment therapy is needed due to hypoxemia;
3. The subjects or their families signed informed consent.
4. Admission to ICU was less than 72 hours;
5. The estimated duration of mechanical ventilation was more than or equal to 48 hours;
6. Age ≥ 18 years old and ≤ 80 years old;

Exclusion Criteria

1. The patients with heart implants could not be monitored by EIT;
2. Patients or their families refused to participate in the study;
3. Hypernatremia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
EIT-guided group	EIT-guided PEEP setting	Treatment based on EIT
Control group	ARDS-net PEEP setting	Treatment based on ARDS-net Peep setting

Primary Outcome Measures

Name	Time	Method
ventilation free days	1 Day

Secondary Outcome Measures

Name	Time	Method
28-day mortality	28 days

Trial Locations

Locations (1)

Peking Union Medical College Hospital; 🇨🇳 Beijing, Beijing, China