A Clinical study of enema with Medicated decoction & Modern treatment regime in the management of joint pain.

Not yet recruiting

Conditions: Deformity of finger(s). Ayurveda Condition: AMAVATAH, (2) ICD-10 Condition: M20-M25||Other joint disorders. Ayurveda Condition: AMAVATAH,

Registration Number: CTRI/2023/06/053786

Lead Sponsor: Department of Kayachikitsa Faculty of Ayurveda IMS BHU

Brief Summary: Rheumatoid arthritis is the most common chronic, immune -inflammatory systemic disease. In india the prevalence of RA is 0.65% -0.75% according to API. Although the etiology and pathogenesis of RA is not clear but its presumed that autoimmunity plays a significant role in the genesis of disease, Chronicity and progression of RA. The conventional medical management is always challenged by the poor response, adverse effects, invasive complications. in this study, will evaluate the importance of anti-rheumatic drug induced host microbiota modulations and possible probiotics that can generate eubiosis. The present clinical study aim to assess clinically the efficacy of Erandathi Kwatha with Vaitharana vasti and Modern treatment regime in the management of Amavata(RA) with special reference to Gut microbiota. There will be 3 month duration with monthly follow up with medication. Assessment will be done on the basis of prepared proforma for subjective and objective parameters.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 90

Inclusion Criteria

1.Patients aged between 16 â€“ 60 years age.
2.Diagnosed cases of Amavata/RA based on symptoms and signs described in Madava Nidana & ACR 2010 3.Patients with H/O more than 1 year with established disease.
4.Sero positive and sero negative both cases are included.

Exclusion Criteria

1.Patients below the age of 16 and above 60 years of age 2.Patients suffering from systemic disorders (like Diabetes Mellitus, Cardiac diseases, Pulmonary Tuberculosis, Essential Hypertension, SLE, Infectious Arthritis, Hypertrophic Arthropathy) 3.Pregnant & Lactating women.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sparsahatwa & Jwara	Three months with monthly follow up
Relief in Sandhisoola	Three months with monthly follow up
Sandhisotha	Three months with monthly follow up
Sandhigraha	Three months with monthly follow up

Secondary Outcome Measures

Name	Time	Method
Assessment of-	1 Laboratory parameters

Trial Locations

Locations (1): Sir Sunderlal Hospital BHU
🇮🇳
Varanasi, UTTAR PRADESH, India
Sir Sunderlal Hospital BHU
🇮🇳Varanasi, UTTAR PRADESH, India
Prof O P Singh
Principal investigator
9415818732
singhopbhu@gmail.com