Effectiveness of intraosseous tranexamic acid combined with intravenous tranexamic acid in hip arthroplasty

Phase 4

• Conditions: Osteoarthritis of hip; Hip arthroplasty

• Registration Number: TCTR20200511002
• Lead Sponsor: arathorn Kongsakpaisal

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-11
• Study Completion: 2020-10-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Adult patients diagnoses as osteoarthritis of hip and undergoing cementless total hip arthroplasty

Exclusion Criteria

- Allergy to tranexamic acid
- Coagulopathy
- Severe renal impairment
- History of venous thromboembolism
- History of ischemic heart disease, ischemic stroke
- History of seizure

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total blood loss from total hip arthroplasty 3 days Intraoperative blood loss+ Drainage+ Hb change

Secondary Outcome Measures

Name	Time	Method
Complications : venous thromboembolism 1 week Monitor sign and symptoms of VTE, if suspect, then further investigations will be done.