MATADOR: Minimising Adaptive Thermogenesis And Deactivating Obesity Rebound

Not Applicable

Active, not recruiting

• Conditions: Obesity; Metabolic and Endocrine - Normal metabolism and endocrine development and function; Diet and Nutrition - Obesity

• Registration Number: ACTRN12611001017910
• Lead Sponsor: Professor Nuala Byrne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-09-22
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: Male
• Target Recruitment: 100

Inclusion Criteria

Sedentary (< 60 mins physical activity per week)
Class I or II obese (30-40kg.m-2)
Waist circumference >102 cm
Euthyroid, non-diabetic, ambulatory, and weight stable for at least 6 months (+/-2kg)

Exclusion Criteria

Diabetic or fasting blood glucose > 6.0 mmol/L (from medical screening)
Major surgery that will affect gut function/metabolic rate
Arthritis/musculoskeletal problems that would preclude full participation in all testing/affect activities of daily living
Heart condition
Sleep apnoea
Thyroid condition
Current smoker or gave up smoking within the last 6 months
Any medications known to affect metabolic rate or neuroendocrine function
Non-ambulatory
Currently on a diet” or actively losing weight

Study & Design

• Study Type: Interventional
• Study Design: Not specified