Pilot study on the effect of different dietary fatty acids on impaired glucose tolerance in obese urban Gambian wome
Not Applicable
Completed
- Conditions
- Obesity-related disease, non-insulin dependent diabetes mellitusNutritional, Metabolic, EndocrineNon-insulin-dependent diabetes mellitus
- Registration Number
- ISRCTN24376821
- Lead Sponsor
- Medical Research Council (MRC) (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 61
Inclusion Criteria
1. Female living in Bakau (urban area in the Gambia)
2. Aged 30 years or older
3. Being obese i.e. having a body mass index more than or equal to 27 kg/m^2
4. Having an impaired glucose tolerance (oral glucose tolerance test; 120-minute glucose between 6.7 and 10.0 mmol/l)
5. Subjects consent
Exclusion Criteria
Subjects diagnosed as diabetic by their doctor or on medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> Outcomes were measured before baseline, at baseline, at three and six months of the intervention:<br> 1. Full plasma and adipose tissue fatty acid analysis<br> 2. Fasting glucose<br> 3. Fasting insulin<br> 4. Oral glucose tolerance test<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Anthropometric measurements (fat mass and fat free mass, waist-to-hip ratio)<br> 2. Diastolic and systolic blood pressure<br> 3. Full lipid profile<br> 4. Plasma Tumour Necrosis Factor (TNF)alpha and receptors<br> 5. Plasma InterLeukin-6 (IL-6) and receptors<br> 6. Sialic acid<br>