Skip to main content
Clinical Trials/NCT06161857
NCT06161857
Recruiting
Not Applicable

Auditory Brainstem Response Thresholds at 6 and 8KHz in Adults With Normal Hearing and Sensorineural Hearing Loss

Cardiff and Vale University Health Board1 site in 1 country40 target enrollmentDecember 18, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hearing Loss, High-Frequency
Sponsor
Cardiff and Vale University Health Board
Enrollment
40
Locations
1
Primary Endpoint
Difference between ABR and PTA thresholds
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

This study is looking at a method called 'ABR', which measures the electrical activity in the brain (brain waves) when we hear sounds. This study will look at the electrical activity in participants brains in response to high-pitched sounds. First, the investigators will find the quietest sounds the participants can hear. Then the investigators will use 'ABR' to measure the quietest sounds that trigger electrical activity in participants brains'. This is to find out if there is a difference between the quietest sounds participants can hear, and the quietest sounds that trigger these brain waves. We are also interested in finding out if having a hearing loss affects this.

Detailed Description

The most common way of measuring how good someone's hearing is, is to play them sounds at different levels and ask them to respond when they can hear it, for example, by pressing a button when they hear a sound. However, some people such as young children and people with learning disabilities can't do this. So, we may use the ABR technique instead. However, there are usually differences between ABR thresholds (the quietest level of sound needed to trigger an electrical response in the brain) and behavioural hearing level thresholds (the quietest level sound is perceived). If we know what this difference usually is, we can use ABR to work out how good someone's hearing is. We can already do this for most of the important pitches (aka frequencies) of sound, as typically experienced in the muffled sound in telephones. But we do not know the difference between ABR and behavioural thresholds for high-pitched sounds that help make hearing crisper. So, that is what this study is trying to find out. To do this we need people with different hearing levels to participate in our study. Including people with normal hearing and people with a hearing loss. We aim to recruit nearly 40 people in total with a range of different hearing levels.

Registry
clinicaltrials.gov
Start Date
December 18, 2023
End Date
June 2024
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Participant is able and willing to give informed consent.
  • Participant is over
  • Hearing in the test ear of ≤90dBSPL at 6 kHz and 8 kHz in PTA
  • Able and willing to perform PTA reliably.
  • Able and willing to sit still comfortably for the duration of an ABR.

Exclusion Criteria

  • Any conductive element to hearing loss (air-bone gap on PTA of \>10dB).
  • Occluding wax, TM perforations or ear infections (on otoscopy)
  • CI or BAHA user
  • Abnormal outer of middle ear

Outcomes

Primary Outcomes

Difference between ABR and PTA thresholds

Time Frame: through study completion, 4-5 months

Compare ABR thresholds to PTA thresholds at 6 and 8 kHz in normal hearing adults and adults with sensorineural hearing loss.

Secondary Outcomes

  • Effect of participants hearing level on ABR-PTA threshold differences(through study completion, 4-5 months)

Study Sites (1)

Loading locations...

Similar Trials