Screening for Autism Spectrum Disorders Using Auditory Brainstem Responses
- Conditions
- Autism Spectrum Disorder
- Registration Number
- NCT03971578
- Lead Sponsor
- Intelligent Hearing Systems
- Brief Summary
The purpose of this study is to develop an Auditory Brainstem Response (ABR) based neurological screening method to detect increased risk for Autism Spectrum Disorders (ASD) and other neurological conditions in newborns.
- Detailed Description
In the proposed study, a screening method for neurological deficits, with an emphasis on its application to ASD, will be developed and its feasibility demonstrated. The proposed method will utilize high rate stimulation to acquire Auditory Brainstem Responses in order to determine peak latency and amplitude differences in children with ASD compared to non-ASD. Similarly to newborn hearing screening, the output of the screening method will provide an automated pass or refer outcome that can be used by a physician to determine if the child needs further evaluation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 81
- Children with autism spectrum disorder diagnosis
- Normally developing age- and gender-matched controls
- Permanent or temporary hearing loss at the time of testing.
- Craniofacial abnormalities
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ABR Peak V Latency One Week Auditory Brainstem Response (ABR) peak V latency measurement for the five stimulation rates used in the study. The latency is the time, measured in ms, from the onset of the stimulus to the generation of the response peak component. ABR peak V is the most prominent response peak component in humans.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Miami Department of Psychology
🇺🇸Coral Gables, Florida, United States
University of Miami Department of Psychology🇺🇸Coral Gables, Florida, United States