Autism Spectrum Disorders: Clinical and Neurophysiological Evolutions Through a Functional Rehabilitation of Social Communication
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Clinical changes between Baseline and Two years
研究概览
简要总结
This study aims to identify clinical and biological markers which would allow to evaluate precisely the evolution of children with autism spectrum disorders throughout intervention.
详细描述
200 children with autism spectrum disorders (1-12 years old) will be included in a 2 years follow-up study. Both clinical and neurophysiological evaluations (electrophysiological and eye tracking) will be completed at different times of the follow-up. This integrative approach, combining clinical and biological markers, will allow the identification of different developmental trajectories and then a better individuation of treatment in autism spectrum disorders.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Months 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •re-education of social communication
排除标准
- •multi-handicapped associated to ASD
结局指标
主要结局
Clinical changes between Baseline and Two years
时间窗: 2 years
Autism Diagnostic Observation Schedule (ADOS)
次要结局
- Social and cognitive évaluations at 1 year(1 year)
- neurophysiological evaluations at baseline(baseline)
- neurophysiological evaluations at 1 year(1 year)
- neurophysiological évaluations at 2 years(2 years)
- Social and cognitive evaluations at baseline(baseline)
- Social and cognitive évaluations at 2 years(1 year)
- Repetitive behaviors évaluations at baseline(baseline)
- Repetitive behaviors évaluations at one year(1 year)
- Repetitive behaviors at two years(2 years)