Autism Spectrum Disorders: Clinical and Neurophysiological Evolutions Through a Functional Rehabilitation of Social Communication
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Autistic Disorder
- Sponsor
- University Hospital, Tours
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Clinical changes between Baseline and Two years
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
This study aims to identify clinical and biological markers which would allow to evaluate precisely the evolution of children with autism spectrum disorders throughout intervention.
Detailed Description
200 children with autism spectrum disorders (1-12 years old) will be included in a 2 years follow-up study. Both clinical and neurophysiological evaluations (electrophysiological and eye tracking) will be completed at different times of the follow-up. This integrative approach, combining clinical and biological markers, will allow the identification of different developmental trajectories and then a better individuation of treatment in autism spectrum disorders.
Investigators
Eligibility Criteria
Inclusion Criteria
- •re-education of social communication
Exclusion Criteria
- •multi-handicapped associated to ASD
Outcomes
Primary Outcomes
Clinical changes between Baseline and Two years
Time Frame: 2 years
Autism Diagnostic Observation Schedule (ADOS)
Secondary Outcomes
- Social and cognitive évaluations at 1 year(1 year)
- neurophysiological evaluations at baseline(baseline)
- neurophysiological evaluations at 1 year(1 year)
- neurophysiological évaluations at 2 years(2 years)
- Social and cognitive evaluations at baseline(baseline)
- Social and cognitive évaluations at 2 years(1 year)
- Repetitive behaviors évaluations at baseline(baseline)
- Repetitive behaviors évaluations at one year(1 year)
- Repetitive behaviors at two years(2 years)