FuRST 2.0 Cognitive Pre-Testing
- Conditions
- Huntington's Disease
- Registration Number
- NCT02881931
- Lead Sponsor
- CHDI Foundation, Inc.
- Brief Summary
The FuRST 2.0 scale is being developed as a Patient Reported Outcome (PRO) with information coming directly from the Huntington's Disease Gene Expansion Carrier (HDGEC) and companion through self-report. The purpose of this study is to identify real or potential comprehension or usage problems with questionnaire items or response options. Through a process of structured cognitive de-briefing with HDGEC participants and companions, independently, followed by qualitative analysis, the final phrasing of the individual items and response options for the scale will be generated. Depending on the results of the first round of cognitive pre-testing, additional rounds of cognitive pre-testing may be required.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 75
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Participants' comprehension of the FuRST 2.0 rating scale measured by qualitative analysis 8 months The primary assessment will use qualitative analysis of the cognitive interview to determine the usability of the FuRST 2.0 scale in the HD population.
- Secondary Outcome Measures
Name Time Method The difference between the ratings of the HDGEC participants and the companions measured by the FuRST 2.0 rating scale 8 months The secondary outcome measure will be evaluated using the Kolmogorov-Smirnov test
Trial Locations
- Locations (4)
Rocky Mountain Movement Disorders Center, P.C.
🇺🇸Englewood, Colorado, United States
Hereditary Neurology Disease Centre, Inc.
🇺🇸Wichita, Kansas, United States
Columbia University
🇺🇸New York, New York, United States
CENTRE FOR MOVEMENT DISORDERS (Neuropharm Consulting)
🇨🇦Toronto, Ontario, Canada
Rocky Mountain Movement Disorders Center, P.C.🇺🇸Englewood, Colorado, United States