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Clinical Trials/NCT05898607
NCT05898607
Completed
Not Applicable

Continuous Ultrasound Guided Erector Spinae Plane Block vs Thoracic Paravertebral Block for Postoperative Analgesia in Patients Undergoing Thoractomy

Amal Gouda Elsayed Safan1 site in 1 country40 target enrollmentFebruary 10, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Amal Gouda Elsayed Safan
Enrollment
40
Locations
1
Primary Endpoint
Compare the VAS score postoperative of (U/S)-guided continuous (ESPB) to continuous (TPVB) following thoracotomy
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

in this study the investigators will investigate and compare the analgesic efficacy of two techniques (continuous TPVB and continuous ESPB) in relieving thoracotomy pain

Detailed Description

General Anesthesia will be induced with Fentanyl (1-2 μg/kg), Propofol (2-3 mg/kg), and Atracurium (0.5-0.8 mg/kg). Pressure controlled Volume guarantee Ventilation mode will be used to maintain O2 Saturation Above 98% and End tidal co2 Around 30-35 mmHg. Anesthesia will be maintained with Isoflurane 1.2 Minimum Alveolar Concentration inhalation after induction Group A: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous infusion U/S-Guided TPVB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative and Group B: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous U/S-Guided ESPB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative.

Registry
clinicaltrials.gov
Start Date
February 10, 2023
End Date
January 25, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Amal Gouda Elsayed Safan
Responsible Party
Sponsor Investigator
Principal Investigator

Amal Gouda Elsayed Safan

lecturer of anaethesia

Menoufia University

Eligibility Criteria

Inclusion Criteria

  • Eligible 40 patients will be older than 21 years old with American society of anesthesia physical status I\& II scheduled for elective thoracotomy

Exclusion Criteria

  • Patients who are:
  • Uncooperative.
  • Having allergy to any of the study drugs.
  • Known abuse of alcohol or medication.
  • Having Local infection at the site of injection or systemic infection.
  • Pregnancy.
  • With coagulation disorders or on anticoagulation therapy

Outcomes

Primary Outcomes

Compare the VAS score postoperative of (U/S)-guided continuous (ESPB) to continuous (TPVB) following thoracotomy

Time Frame: 48 hours

visual analogue scale (VAS) Score

Secondary Outcomes

  • occurrence of adverse events(24hours)
  • 1 st call analgesia(1 hour)
  • Total rescue opioid dose used(48 hour)
  • patient satisfaction at 24 hours(24 hours)
  • hospital stay(1 week)

Study Sites (1)

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