Impact of Endometriosis on Pregnancy and Delivery - a Retrospective Cohort Study

Completed

• Conditions: Endometriosis; Pregnancy Complications; Delivery Complication; Complication; Miscarriage
• Interventions: Other: questionnaire

• Registration Number: NCT04664335
• Lead Sponsor: University Hospital Muenster

Brief Summary

Purpose:

To study the impact of endometriosis on subsequent pregnancy and delivery.

Methods:

retrospective analysis by questionnaire / interview of cases (endometriosis laparoscopically removed / child wish) vs. controls (endometriosis laparoscopically excluded / child wish) from the University Hospital Muenster, Germany, treated between 2009 and 2016; analysis of pregnancy rate, mode of delivery and complications using Clavien-Dindo-classification, role of deep infiltrating endometriosis using ENZIAN classification; data analysis using t-test with p \< 0.050% being considered significant.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-12-01
• Primary Completion: 2019-12-01
• Study Completion: 2020-12-01
• Study First Submitted: 2020-12-04
• Study First Submitted QC: 2020-12-10
• Study First Posted: 2020-12-11
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-19
• Last Update Posted: 2022-08-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 1762

Inclusion Criteria

• cases: Operation because of endometriosis at the endometriosis Center, University Hospital Muenster, child wish, wants to participate, correct age group
• controls: Operation because of sterility, exclusion of endometriosis during this Operation, child wish, wants to participate, correct age group

Exclusion Criteria

• cases / controls: declines participation, incorrect age Group, no child wish

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
controls	questionnaire	endometriosis laparoscopically excluded / child wish
endometriosis cases	questionnaire	endometriosis laparoscopically removed / child wish

Primary Outcome Measures

Name	Time	Method
pregnancy rate	through study completion, an average of 1 year	pregnancy rate
complications	through study completion, an average of 1 year	complications during pregnancy, delivery, puerperium

Trial Locations

Locations (1)

University Hospital Münster Germany; 🇩🇪 Münster, NRW, Germany