The effect of dietary salt intake on proximal tubular endocytic functio

Completed

• Conditions: 10029149; proteinuria; urinary protein loss

• Registration Number: NL-OMON45413
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 8

Inclusion Criteria

- Age 18-30 years
- Male sex

Exclusion Criteria

- Use of any medication
- Smoking
- History of hypertension, cardiovascular / metabolic / renal / urogenital / hepatic disease, substance abuse
- eGFR < 90 mL/min/1.73 m2 (calculated using the CKD-EPI equation)
- Albuminuria > 20 mg/10 mmol creatinine in spot urine
- Hypertension at screening visit (>140/90 mmHg by office blood pressure measurement)
- Urinary tract infection at screening visit
- Participation in evening or night shift work during the study period and the week before enrolment
- BMI > 27 kg/m2
- Inability to adhere to the study protocol (due to language or cognitive disability)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Proximal tubular endocytic function.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Blood pressure, RAS components, kidney function, serum and urine electrolytes,<br /><br>body fluid composition</p><br>