Acute effects of dietary salt intake on blood vessel functio

Not Applicable

Completed

• Conditions: Endothelial function; Cardiovascular - Normal development and function of the cardiovascular system; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12610000124033
• Lead Sponsor: Commonwealth Scientific and Industrial Research Organisation (CSIRO): Food and Nutritional Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-02-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

Body Mass Index (BMI) > 18.5 kg/m2
Systolic blood pressure <130mmHg
Diastolic blood pressure <90mmHg
Weight stable over the past 6 months

Exclusion Criteria

Know metabolic disease such as liver or kidney disease
Treated hypertension
Previous clinical cardiovascular disease
Use of non-steroidal anti-inflammatory drugs, folate supplementation or systemic steroids
Significant weight loss (>5% body weight) in preceding 6 months
Unable to comprehend study protocol

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in endothelial function as measured by flow-mediated dilatation (%)[Flow-mediated dilatation is measured at each of the following time points: Baseline (15 minutes before test meal consumption); post meal consumption at 30minutes; 60minutes; 90minutes; 120minutes]

Secondary Outcome Measures

Name	Time	Method
Change in endothelial function as measured by Reactive Hyperaemia-Peripheral Artery Tonometry (RH-PAT)[Baseline (15 minutes before test meal consumption); post meal consumption at 30minutes; 60minutes; 90minutes; 120minutes];Change in blood pressure (mmHg) as measured with sphygmomanometer[Baseline (15 minutes before test meal consumption); post meal consumption at 30minutes; 60minutes; 90minutes; 120minutes]