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Clinical Trials/NCT00957021
NCT00957021
Completed
Not Applicable

A Prospective, Post-market, Multi-center Study of the Outcomes of the Triathlon® Posteriorly Stabilized (PS) Total Knee System

Stryker Orthopaedics11 sites in 1 country409 target enrollmentDecember 2005

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Arthroplasty, Replacement, Knee
Sponsor
Stryker Orthopaedics
Enrollment
409
Locations
11
Primary Endpoint
Range of Motion
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the clinical outcomes (range of motion, pain, function, radiographic stability, and health related quality of life) of patients receiving the Triathlon® Posterior Stabilized (PS) Total Knee System. These outcomes will be evaluated using pre-operative scores and comparing them to post-operative scores in addition to being compared with cases who received the Scorpio® PS implant.

Detailed Description

The Triathlon® Posteriorly Stabilized (PS) Total Knee System components are for use in cemented total knee arthroplasty for painful, disabling joint disease of the knee resulting from non-inflammatory degenerative joint disease (including osteoarthritis, traumatic arthritis or avascular necrosis) or rheumatoid arthritis (excluded from this study according to protocol). The components are designed to improve range of motion (ROM) and stability. This study serves to demonstrate that subjects have reduced pain, increased ROM and improved stability following implantation with the Triathlon® PS Total Knee System.

Registry
clinicaltrials.gov
Start Date
December 2005
End Date
January 2014
Last Updated
9 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The subject is a male or non-pregnant female 21-80 years of age at the time of enrollment.
  • The subject requires a primary cemented total knee replacement.
  • The subject has a diagnosis of osteoarthritis (OA), traumatic arthritis (TA), or avascular necrosis (AVN).
  • The subject has intact collateral ligaments.
  • The subject has signed the IRB approved, study specific Informed Patient Consent Form.
  • The subject is willing and able to comply with postoperative scheduled clinical and radiographic evaluations and rehabilitation.

Exclusion Criteria

  • The subject has inflammatory arthritis.
  • The subject is morbidly obese, BMI \>
  • The subject has a history of total or unicompartmental reconstruction of the affected joint.
  • The subject has had a high tibial osteotomy or femoral osteotomy.
  • The subject has a neuromuscular or neurosensory deficiency that would limit the ability to assess the performance of the device.
  • The subject has a systemic or metabolic disorder leading to progressive bone deterioration.
  • The subject is immunologically suppressed, or receiving chronic steroids (\>30 days duration).
  • The subject's bone stock is compromised by disease or infection and cannot provide adequate support and/or fixation to the prosthesis.
  • The subject has had a knee fusion at the affected joint.
  • The subject has an active or suspected latent infection in or about the knee joint.

Outcomes

Primary Outcomes

Range of Motion

Time Frame: 2 years

The primary outcome of this study is to compare active range of motion values for the Triathlon PS Total Knee System.

Secondary Outcomes

  • Patient Outcome Knee Society Score(1,2 and 5 years)
  • Patient Outcome SF-36(1,2,3,4 and 5 years)
  • Patient Outcome Lower-Extremity Activity Scale(1,2,3,4 and 5 years)
  • Patient Outcome WOMAC(5 years)
  • Radiographic Outcome(1,2 and 5 years)

Study Sites (11)

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