A study to see the added effect of Trunapanchmuladighrita and Gokshurachurna in treating mootrashmari

Phase 2/3

Not yet recruiting

• Conditions: Calculus of urinary tract in diseases classified elsewhere. Ayurveda Condition: MUTRAVAHASROTOVIKARAH,

• Registration Number: CTRI/2025/06/088707
• Lead Sponsor: Tilak Ayurved Mahavidyalaya, Pune

Brief Summary

Objective

To evaluate the efficacy of Trunapanchmuladi Ghrita combined with Gokshura Churna versus Gokshura Churna alone in treating Mootrashmari (urinary stones).

Study Design

Open, randomized controlled clinical trial

Duration 28 days

Sample size: 64 participants   32 per group

Participants:

Adults aged 18–60 with non-obstructive ureteric calculi (4–7 mm)

Exclusions include systemic illnesses, pregnancy, and congenital kidney anomalies

Interventions:

Group A: Trunapanchmuladi Ghrita + Gokshura Churna

Group B: Gokshura Churna alone

Both groups advised pathya-apathya and hydration

Assessment Parameters:

Subjective: Pain, burning micturition, hematuria

Objective: Size, site, and number of stones via USG

Statistical analysis: Wilcoxon Signed Rank Test, Unpaired t-test

Rationale:

Ayurveda offers promising and cost-effective alternatives to conventional treatments for kidney stones, which often recur after modern interventions.

Expected Outcome:

To determine whether the add-on therapy provides statistically and clinically significant improvement in symptom relief and stone reduction.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-06-18
• Last Update Posted: 2025-07-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Size of calculus-A known diagnosed case of Non obstructive ureteric calculus 4 to 7 mm.
• Age group -18 to 60 years with irrespective of gender.

Exclusion Criteria

• Participants who are suffering from severe systemic disorders like renal failure, Carcinoma Known case of DM, HTN, Asthma, HIV, HbsAg 2.Congenital anomalies of kidney.
• 3.The pregnant women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Efficacy of Trunapanchmuladi ghrita with Gokshura churna in managing Mootrashmari, assessed by reduction in symptom severity scores and overall treatment response.	1st follow up after 7 days and then 14 days and 28 days

Secondary Outcome Measures

Name	Time	Method
1. Reduction in Calculus Size and Expulsion:	Change in size of urinary calculi (measured via imaging techniques like ultrasound or CT).

Trial Locations

Locations (1)

Tilak Ayurved Mahavidyalaya and Seth Tarachand Ramnath Charitable Ayurvedic Hospital; 🇮🇳 Pune, MAHARASHTRA, India

Tilak Ayurved Mahavidyalaya and Seth Tarachand Ramnath Charitable Ayurvedic Hospital

🇮🇳Pune, MAHARASHTRA, India

Dr Akshay Haribhau Devarkar

Principal investigator

8698072410

devarkarakshay81@gmail.com