Efficacy of a Physical and Respiratory Rehabilitation Program (COPERIA-REHAB) for Patients With Persistent COVID-19 (SARS-CoV-2).
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- SARS-CoV-2 Infection
- Sponsor
- Fundacin Biomedica Galicia Sur
- Enrollment
- 56
- Locations
- 4
- Primary Endpoint
- Six Minutes Walking test
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
The pandemic caused by SARS-CoV-2 infection has resulted, in addition to the well-known acute symptoms, in the emergence of a plethora of persistent, diffuse and heterogeneous symptoms such as fatigue, shortness of breath and cognitive dysfunction among others, that have come to be called persistent COVID. Patients have reported that physical activity, stress and sleep disturbances often trigger exacerbations of their symptoms related by some authors to the so-called Post Exertional Malaise (PEM) characteristic of Myalgic Encephalomyelitis. Similarly, by analogy with other pathologies, it has been hypothesized that optimal exercise prescription would benefit these people with persistent COVID-19 symptoms but in practice, the rehabilitation of these patients runs the risk of collapsing respiratory and physical rehabilitation services.
This is why COPERIA proposes the construction of a platform for respiratory, cardiac and muscular telerehabilitation, to compare with face-to-face rehabilitation treatment and to try to predict the influence of physical activity in the prediction of PEM.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age ≥18 and ≤70 years of age.
- •Patients with a diagnosis according to WHO criteria of persistent COVID-19 until 03/28/2022
- •Patients with a Post Covid Functional Status (PCFS) ≥
- •Patients who present a need for physical rehabilitation and agree to perform it.
- •Patients with capacity to consent and who agree to participate in the study.
- •Patients who know how to use Smartphone and/or Tablet and have at least one of these devices.
- •Patients who have access to the rehabilitation tools at home or are willing to go to the gyms proposed in the study to perform the rehabilitation exercises.
Exclusion Criteria
- •Minors or persons judicially incapacitated.
- •Previous neurological or psychiatric pathology involving neuropsychological compromise.
- •Active Covid19 infection.
- •Home oxygen therapy \> 16 hours or home Cpap- Bipap.
- •Previous diagnosis of arrhythmia or blockage.
- •Previous coronary pathology.
- •Decompensated renal or metabolic disease.
- •Signs or symptoms of unknown cardiac disease.
- •Undergoing another physical or cognitive rehabilitation process at the time of inclusion.
- •Patients who do not agree to participate in the study.
Outcomes
Primary Outcomes
Six Minutes Walking test
Time Frame: 8 weeks
The 6-min walk test is a standard in cardiac rehabilitation, serving both to ecologically determine the patient's functional status and to make recommendations regarding the intensity of rehabilitative exercise. The patient is asked to run the maximum distance he/she can in 6 minutes. The length of one of the hospital corridors has been previously measured so that by counting the number of times the patient walks the distance covered is determined. In addition to the number of meters, the heart rate is monitored by means of a pectoral band, and the saturation level by means of a pulse oximeter; the BP is evaluated before and after the test. In the context of functional assessment of Persistent COVID, it has been used for the evaluation of the impact of rehabilitation measures.
Secondary Outcomes
- Maximal Handgrip Strenght(8 weeks)
- Insomnia Severity Index.(8 weeks)
- P maximal inspiratory and P maximal expiratory(8 weeks)
- mMRC dyspnea scale(8 weeks)
- SF-36 Health Questionnaire(8 weeks)
- 1 Minute Sit to Stand test(8 weeks)