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A clinical trial to study the effects of estradiol as compared to EMLA cream on pain due to puncturing the vein and easiness during inserting cannula in obese female patients.

Not Applicable
Conditions
Health Condition 1: null- Pts of ASA I& II,Female pts undergoing any elective surgery,Age between 25 -65 years,Body Mass Index 30kg/mt2,Hemodynamically stable.
Registration Number
CTRI/2014/11/005162
Lead Sponsor
A
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
132
Inclusion Criteria

Pts of ASA I& II,

Female pts undergoing any elective surgery,

Age between 25 -65 years,

Body Mass Index > 30kg/mt2,

Hemodynamically stable,

Exclusion Criteria

Pts with a h/o HTN, DM, Liver disease, Renal Failure, peripheral neuropathy, psychiatric disorders.

Pts on sedatives, hypnotics, antidepressants, estradiol, analgesic & drugs with effects on the nervous system.

Pts allergic to estradiol.

Patientâ??s refusal.

Abnormal skin condition (broken skin, infection, scar psoriasis, eczema) at the site of VP.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence & severity of Venous cannulation pain and number of first attempt failure.Timepoint: immediatly after venous cannulation.
Secondary Outcome Measures
NameTimeMethod
incidence of side effects.Timepoint: for 24 hrs
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