To study incidence and evolution of cardiovascular changes in Mucor mycosis infection at a tertiary care centre in North India
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Total cardiovascular events in the group
Study Overview
Brief Summary
Mucormycosis is an invasive fungal infection . In immunocompromised patients they cause vascular invasion and infarction of organs. Cardiac involvement in the form of myocarditis, angio invasive mucormycosis causing acute coronary syndrome has been reported. We planned an observational study to find out incidence and range of cardiovascular involvement in mucormycosis patients. We take both retrospective and prospective data. We do baseline ECG , echocardiography , cardiac biomarkers and follow them up for 3 months post hospitalisation. We look for any cardiovascular involvement , acute coronary syndrome , arrhythmias during hospitalisation and follow up.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 80.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •age greater than 18 years nucor cases reporting to cardiology out patient department valid informed consent.
Exclusion Criteria
- •not giving consent.
Outcomes
Primary Outcomes
Total cardiovascular events in the group
Time Frame: 4 weeks after presentation
Secondary Outcomes
- Incidence of acute myocardial events in Mucormycosis population 
at baseline and during hospital stay(30 days)
- Myocarditis or myocardial infarction or stenosis detected with ST segment elevation or depression associated with troponin elevation and echocardiography(30 days post hospital admission)
- Characterization of inflammation on cardio-vascular outcomes(30 days post hospital admission)
- New onset cardiac arrhythmia(30 days post hospital admission)
