跳至主要内容
临床试验/CTRI/2022/04/041778
CTRI/2022/04/041778尚未招募不适用

To study incidence and evolution of cardiovascular changes in Mucor mycosis infection at a tertiary care centre in North India

All India Institute of Medical Science Bathinda1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2022年4月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
200
试验地点
1
主要终点
Total cardiovascular events in the group

研究概览

简要总结

Mucormycosis is an invasive fungal infection . In immunocompromised patients they cause vascular invasion and infarction of organs. Cardiac involvement in the form of myocarditis, angio invasive mucormycosis causing acute coronary syndrome has been reported. We planned an observational study to find out incidence and range of cardiovascular involvement in mucormycosis patients. We take both retrospective and prospective data. We do baseline ECG , echocardiography , cardiac biomarkers and  follow them up for 3 months post hospitalisation. We look for any cardiovascular involvement , acute coronary syndrome , arrhythmias during hospitalisation and follow up.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • age greater than 18 years nucor cases reporting to cardiology out patient department valid informed consent.

排除标准

  • not giving consent.

结局指标

主要结局

Total cardiovascular events in the group

时间窗: 4 weeks after presentation

次要结局

  • Incidence of acute myocardial events in Mucormycosis population 
at baseline and during hospital stay(30 days)
  • Myocarditis or myocardial infarction or stenosis detected with ST segment elevation or depression associated with troponin elevation and echocardiography(30 days post hospital admission)
  • Characterization of inflammation on cardio-vascular outcomes(30 days post hospital admission)
  • New onset cardiac arrhythmia(30 days post hospital admission)

研究者

发起方
All India Institute of Medical Science Bathinda
申办方类型
Government medical college

研究点 (1)

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