Mucormycosis related cardiovascular changes study

Not yet recruiting

• Conditions: Unspecified mycosis,

• Registration Number: CTRI/2022/04/041778
• Lead Sponsor: All India Institute of Medical Science Bathinda

Brief Summary

Mucormycosis is an invasive fungal infection . In immunocompromised patients they cause vascular invasion and infarction of organs. Cardiac involvement in the form of myocarditis, angio invasive mucormycosis causing acute coronary syndrome has been reported. We planned an observational study to find out incidence and range of cardiovascular involvement in mucormycosis patients. We take both retrospective and prospective data. We do baseline ECG , echocardiography , cardiac biomarkers and  follow them up for 3 months post hospitalisation. We look for any cardiovascular involvement , acute coronary syndrome , arrhythmias during hospitalisation and follow up.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-15
• Last Update Posted: 2022-10-04

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

age greater than 18 years nucor cases reporting to cardiology out patient department valid informed consent.

Exclusion Criteria

not giving consent.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total cardiovascular events in the group	4 weeks after presentation

Secondary Outcome Measures

Name	Time	Method
New onset cardiac arrhythmia	30 days post hospital admission
Incidence of acute myocardial events in Mucormycosis population 
at baseline and during hospital stay	30 days
Myocarditis or myocardial infarction or stenosis detected with ST segment elevation or depression associated with troponin elevation and echocardiography	30 days post hospital admission
Characterization of inflammation on cardio-vascular outcomes	30 days post hospital admission

Trial Locations

Locations (1)

All india Institute of Medical Science Bathinda; 🇮🇳 Bathinda, PUNJAB, India

All india Institute of Medical Science Bathinda

🇮🇳Bathinda, PUNJAB, India

Dr Rohit Walia

Principal investigator

8800492549

rwalia7731@yahoo.in