Perioperative Fluid Therapy Optimization in Spinal Surgery Using Non-invasive Measurement of Haemodynamics (ClearSight System, Edwards); a Comparison to Standard Method
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hypovolemia
- Sponsor
- University Hospital Hradec Kralove
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- intraoperative fluid balance
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The decision to give fluids perioperatively could be based on methods used to identify preload responsiveness, either invasive or noninvasive estimates of stroke volume variation during mechanical ventilation. This study compares fluid management using continuous noninvasive cardiac output measurement with standard perioperative fluid management.
Detailed Description
The aim of the study is to optimise fluid managemet and to reduce perioperative risks during spinal procedures in prone position. Adequate perioperative management guided by hemodynamic monitoring can help to reduce the risk of complications and thus potentially improve outcomes.
Investigators
Dostalova Vlasta, MD, PhD
Principal Investigator
University Hospital Hradec Kralove
Eligibility Criteria
Inclusion Criteria
- •Glasgow Coma scale 15
- •ASA Physical Status Classification System I-III
- •planed spinal surgery to 3 hours
- •postoperative awakening
- •sinus rhythm
Exclusion Criteria
- •NYHA III, IV
- •BMI over 40 in females and over 35 in men
- •awake operation
- •postoperative artificial ventilation
Outcomes
Primary Outcomes
intraoperative fluid balance
Time Frame: 5 hours
the difference between fluid intake and output and losses during surgery
Secondary Outcomes
- level of creatinine(24 hours)
- mean dose of norepinephrine(5 hours)
- pooperative lung dysfunction(24 hours)
- the length of postoperative stay(till 2 months after surgery)