Single-port thoracoscopic sympathicotomy for treatment of raynaud's phenomenon, a feasibility study.

Completed

• Conditions: Raynaud's disease; 10047075

• Registration Number: NL-OMON46918
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

18-65 years of age
Severe form of RP, defined as clinical need of prostacyclin analogue infusions having been given in the preceding 2 years, without satisfying result OR
Severe form of RP, defined as clinical limiting in everyday life for the patient with presence of a contra-indication for prostacyclin, without satisfying result of standard care.

Exclusion Criteria

- Due to higher risk of complications following unilateral lung-deflation and re-insufflation:
o Known COPD with evidence of emphysematous lung destruction on X-thorax or CT
o History of smoking > 20 pack years
o Lung involvement due to systemic autoimmune disease (based on previously described abnormalities on HRCT or documented pulmonary hypertension by mean pulmonary artery pressure 25 mmHg at rest measured by right heart catherisation).
- Concurrent neurological disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cooling pletysmography<br /><br>Nailbed microscopy</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Quality of life<br /><br>Comlaints diary</p><br>