临床试验/IRCT20151227025726N30

IRCT20151227025726N30尚未招募3 期

Evaluation of the Effectiveness of Two Different Regimens Based on Tosilizumab and Baricitinib in Patients with COVID-19 Respiratory Distress Syndrome

Shahid Beheshti University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2022年3月8日

试验速览

阶段: 3 期
状态: 尚未招募
发起方: Shahid Beheshti University of Medical Sciences
入组人数: 60

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Interventional

入排标准

年龄范围: 18 years 至 100 years（—）
性别: All

入选标准

•Patients between 18 and 100 years old
•Laboratory confirmed COVID-19 with RT-PCR
•Be in severe stage of the disease
•Have signed the consent to participate in the study

排除标准

•Acute or chronic renal failure (Increase in creatinine by more than 3.0 in the last 48 hours or GFR less than 30 mL/min)
•Liver failure (more than 5-fold increase in liver enzymes in asymptomatic patients or more than 3-fold increase in liver enzymes in symptomatic patients or Child Pugh C, D)
•Hypersensitivity reaction to tocilizumab or baricitinib with severe extravasation and symptoms of anaphylactic shock
•Mild stage of the disease
•Pregnant and lactating patients
•Patients who have been intubated
•Patients who are expected to die in the next 48 hours

研究者

发起方

Shahid Beheshti University of Medical Sciences

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Evaluation of the Effectiveness of Two Different... | 临床试验