Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL
- Registration Number
- NCT00784472
- Lead Sponsor
- Katja venborg Pedersen
- Brief Summary
The purpose of this study is to investigate the effect of oxynorm versus morphine after operation for kidney stone (PCNL). In addition the relationship between pain symptoms and referred sensory and trophic changes will be examined in the patients before and after the operation.Finally a blood sample is analysed to investigate pharmaca-genetics.
- Detailed Description
Primary outcome: the amount of opioid (morphine or oxynorm) used the first 4 hours postoperatively.
Secondary outcome: side effect to the opioids, pain score, pain threshold to electrical stimulation and pressure before and after operation, pharmacogenetics, size of referred pain area.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
- Age > 18
- Indication for PCNL
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Exclusion Criteria
- Malignant disease in the upper urinary tract
- Allergy to morphine or oxycodone
- Use of opioids the last 48 hours before PCNL
- Pregnancy
- Nursing mothers
- Present JJ-stent in the ureter
- Previous urinary stone disease on the opposite site
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description oxycodone oxycodone - morphine morphine -
- Primary Outcome Measures
Name Time Method Amount of analgetics used four hours postoperatively
- Secondary Outcome Measures
Name Time Method Side effects four hours postoperatively
Trial Locations
- Locations (1)
Hospital Little Belt, Fredericia
🇩🇰Fredericia, Denmark