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Clinical Trials/NCT05234294
NCT05234294UnknownNot Applicable

Short and Long Term Symptoms After Omicron Infection in the Faroe Islands

Faroese Hospital System1 site in 1 country15,000 target enrollmentStarted: January 31, 2022Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Sponsor
Enrollment
15,000
Locations
1
Primary Endpoint
Long Covid after Omicron

Study Overview

Brief Summary

The COVID-19 pandemic has led to a high disease burden worldwide, both during the acute disease phase and a large group of infected suffering from Long Covid. Long Covid has been subject to a lot of research, even though there is still much not understood. However, the need for time to pass before symptoms can be assessed limits research into Long Covid on a longer timescale.

The worldwide pandemic has shifted after the emergence of the Omicron variant. The number of confirmed COVID cases worldwide has risen to unprecedented levels. Yet, hospitalizations and death do not increase at the same level as with previous variants.

The observed shift in the pandemic with the increasing number of infections with the Omicron variant leads to the urgent question about Long Covid after Omicron infection. This rise has also taken place in the Faroe Islands, with many infections during December 2021 and January 2022. The majority of infections during January 2022 in the Faroe Islands are expected to be of the Omicron variant, presenting the opportunity to investigate symptoms after infection with the Omicron variant.

In this study, we will invite all infected with COVID-19 during January 2022 in the Faroe Islands to answer an online survey regarding symptoms. This survey will be sent out once a month for a total of six times, both focusing on acute symptoms and Long Covid symptoms.

Concurrently, we will send an online survey to Faroese inhabitants recruited in two separate random COVID-19 serological surveys during 2020, which will act as controls.

The knowledge gathered during this study will rapidly bring understanding to the urgent question of Long Covid after Omicron infections. We know that the Omicron variant leads to fewer hospitalizations and death than previous variants, yet the question of Long Covid is still unanswered, and needs rapid answers.

Detailed Description

Objectives Primary objective: To investigate Long Covid symptoms after Omicron infection through monthly surveys for six months, compared to controls not infected.

Secondary objective: To investigate acute symptoms during Omicron infection through the first survey shortly after the infection.

Methods All confirmed COVID-19 patients in January 2022 will receive an invitation to participate in an online survey.

We will send the online surveys in two separate bulks. The individuals with confirmed COVID-19 during the first half of January will receive the online survey first, at the same time as half of the controls. The rest of the COVID-19 cases will receive it during the first half of February, along with the rest of the control group.

Outcomes Self-reported symptoms through the online survey compared to the symptoms in the control group.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Long Covid after Omicron

Time Frame: 6 months

Symptoms gathered through survey

Secondary Outcomes

  • Acute symptoms during Omicron infection(1 month)

Investigators

Sponsor
Faroese Hospital System
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Maria Skaalum Petersen

Phd

Faroese Hospital System

Study Sites (1)

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