Survey of Current Management of Orthopaedic Complications in CMT Patients

Completed

• Conditions: Charcot-Marie-Tooth Disease
• Interventions: Other: Survey

• Registration Number: NCT02001038
• Lead Sponsor: University College London Hospitals

Brief Summary

Charcot-Marie-Tooth (CMT) disease is the most common inherited peripheral neuropathy. Foot deformities are frequent complications in CMT patients and orthopaedic surgery is often required. As yet there are no systematic studies on the management of orthopaedic complications in CMT patients and the current approach varies between centres. This study is a survey with the aim of understanding the current surgical approach to orthopaedic complications in CMT.

The target population includes orthopaedic surgeons who perform surgical procedures for foot deformities in CMT patients attending centres participating in the Inherited Neuropathies Consortium (INC).

Detailed Description

The study protocol consists of a survey addressed to orthopaedic surgeons. The survey will be completed once and it includes two different scenarios of typical CMT patients (one adult and one child).

The orthopaedic surgeons will be asked which surgical procedures they would apply to each scenario:

* forefoot cavus,

* clawtoes and

* hindfoot varus

No medications or therapeutic agents are a component of this project.

Study Timeline

• Study Start: 2013-02
• Study First Submitted: 2013-11-27
• Study First Submitted QC: 2013-12-03
• Study First Posted: 2013-12-04
• Primary Completion: 2014-11
• Study Completion: 2014-11
• Status Verified: 2015-01
• Last Update Submitted: 2015-01-29
• Last Update Posted: 2015-01-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Orthopaedic surgeons who perform surgical procedures for foot deformities in CMT patients attending centres participating in the Inherited Neuropatheis Consortium (INC)
• Willing to complete survey

Exclusion Criteria

• Does not read or speak English
• Inability to provide informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Orthopaedic surgeons	Survey	Orthopaedic surgeons who perform surgical procedures for foot deformities in CMT patients at participants centres.

Primary Outcome Measures

Name	Time	Method
Procedural correlations among orthopaedic surgeons on management of foot deformities in CMT patients	1 day

Trial Locations

Locations (1)

National Hospital for Neurology and Neurosurgery; 🇬🇧 London, United Kingdom