Oral Carvedilol in Escalating Doses in the Acute Treatment of Atrial Fibrillation

Phase 3

Completed

• Conditions: Atrial Fibrillation
• Interventions: Drug: oral carvedilol

• Registration Number: NCT02832089
• Lead Sponsor: Andhra Medical College

Brief Summary

Oral carvedilol administered in escalating doses in patients with atrial fibrillation among patients with AF with fast ventricular rate.

Detailed Description

Patients with AF with FVR of any etiology were evaluated and given escalating doses of oral carvedilol in doses - 3.125mg OD, then 3.125 bid, then 6.25mg bid, then 12.5mg bid. The ECG was recorded regularly and analysed for rate reduction or control.

Study Timeline

• Study Start: 2000-12
• Primary Completion: 2002-03
• Study Completion: 2002-03
• Study First Submitted: 2015-12-28
• Status Verified: 2016-07
• Study First Submitted QC: 2016-07-11
• Last Update Submitted: 2016-07-11
• Study First Posted: 2016-07-14
• Last Update Posted: 2016-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• AF with fast ventricular rate

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
active arm	oral carvedilol	single arm study with one group given oral carvedilol.

Primary Outcome Measures

Name	Time	Method
reduction in ventricular rate in AF patients	24 hours	reduction in ventricular rate in patients with AF and fast ventricular rate.