Preventing depression relapse / recurrence in NHS settings through mindfulness-based cognitive therapy (MBCT). - PREVENT
- Conditions
- Recurrent depression. Patients who have experienced 3 or more episodes of depression and are already taking anti-depressants will be invited to take part in this study.
- Registration Number
- EUCTR2009-012428-10-GB
- Lead Sponsor
- niversity of Exeter
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- 420
Inclusion: A diagnosis of recurrent major depressive disorder in full or partial remission according to the DSM-IV, with 3 or more previous major depressive episodes; aged 18 or older; and on a therapeutic dose of ADM in line with the British National Formulary (BNF) and NICE guidance. We include older adults with depression on the basis of the high prevalence of depression in older adults and a promising pilot study of MBCT with this group (Smith, 2004).
Exclusion: patients who are currently depressed, co-morbid diagnoses of current substance dependence; organic brain damage; current/past psychosis, including bipolar disorder; persistent antisocial behaviour; persistent self-injury requiring clinical management/therapy; and formal concurrent psychotherapy.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Currently depressed, co-morbid diagnoses of current substance dependence; organic brain damage; current/past psychosis, including bipolar disorder; persistent anti-social behaviour; persistent self-injury requiring clinical management/therapy; and formal concurrent psychotherapy.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method