Pain treatment in the Emergency Department
- Conditions
- Acute pain in the Emergency DepartmentMedDRA version: 20.1Level: LLTClassification code 10066714Term: Acute painSystem Organ Class: 100000004867Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2021-005116-64-DK
- Lead Sponsor
- Aarhus University Hospital, Department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 160
1) Emergency Department admission
2) Age = 18 years
3) NRS = 5
4) Stable vital signs defined as systolic blood pressure = 90 mmHg, heart rate between 50 and 150 per minute, respiratory rate between 8 and 30 per minute, oxygen saturation greater than or equal to 92%.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 150
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 10
1) Initial management by trauma-team
2) Systolic blood pressure = 180mmHg, severe untreated arrhythmia, unstable angina, recent myocardial infarction (< 30 days), severe heart-failure (Ejection fraction < 40 %)
3) Symptoms of untreated hyperthyroidism
4) Cirrhosis with ascites
5) Known/suspected pregnancy or breastfeeding
6) Patients for whom consent is not obtainable or psychiatric forced treatment.
7) Previously enrolled in the trial
8) Psychiatric illness prior to admission defined as prior psychosis/schizophrenia
9) Untreated diagnosed glaucoma
10) Known hypersensitivity to ketamine or to any excipient or prior use of ketamine with a negative experience (i.e. hallucinations)
11) Patient clearly influenced by drugs or alcohol
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method