The Effects of Non Harmonic and White Noise on Human Pain Sensitivity: a Study of Healthy Volunteers

Not Applicable

Completed

• Conditions: Pain
• Interventions: Behavioral: noise stimulation

• Registration Number: NCT06165757
• Lead Sponsor: The Second Affiliated Hospital of Chongqing Medical University

Brief Summary

Study the effects of 60dB and 80dB white noise, 50-70dB and 70-90dB non harmonic tones on the basic pain threshold of subjects, including the threshold and tolerance of electrical stimulation pain,the threshold and tolerance of cold pain stimulation, and the threshold and tolerance of tenderness stimulation.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-10
• Study Start: 2023-10-10
• Study First Submitted: 2023-11-09
• Study First Submitted QC: 2023-12-04
• Study First Posted: 2023-12-11
• Primary Completion: 2024-01-20
• Study Completion: 2024-01-20
• Last Update Submitted: 2024-03-11
• Last Update Posted: 2024-03-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Between the ages of 18 and 35, regardless of gender
• No serious chronic diseases
• There is no self-reported history of chronic opioid drug use or neuropathy

Exclusion Criteria

• A history of alcohol or drug abuse
• Pregnant or lactating
• Severe cardiovascular, kidney, or liver diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
noise on pain	noise stimulation	Comparison of pain sensitivity before and after hearing noise among 15 subjects in each group.

Primary Outcome Measures

Name	Time	Method
cold pain sensitivity	from the study beginning to 30 min after the procedure	Each participant was measured using the cold pain threshold and tolerance (tested by immersion the hand in 4℃ water), which lower value present higher pain sensitivity
electrical pain sensitivity	from the study beginning to 30 min after the procedure	Each participant was measured using the cold pain threshold and tolerance (tested by a electrical stimulator), which lower value present higher pain sensitivity
mechanical pain sensitivity	from the study beginning to 30 min after the procedure	Each participant was measured using the pressure pain threshold and tolerance (tested by a pressure meter), which lower value present higher pain sensitivity

Trial Locations

Locations (1)

Department of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University; 🇨🇳 Chongqing, Chongqing, China