A Prospective Observational Comparative Study Of Different Doses Of Remifentanil Infusion On Hemodynamics And Recovery In Children Undergoing Cardiac Catheterization

Remifentanil, a potent and short-acting opioid analgesic, has shown promising results in providing effective pain relief and sedation in various paediatric surgical procedures.

By examining the hemodynamic changes and recovery profiles associated with varying doses of remifentanil, this study aims to contribute valuable insights into the safe and effective use of this opioid analgesic in this particular patient population in cardiac catheterization.

Patients aged 5 years to 12 years undergoing Cardiac Catheterization will be assessed intraoperatively. Study is divided into 2 groups:

Group A -0.1mcg/kg/min and

Group B - 0.2mcg/kg/min.

Hemodynamic changes and recovery will be assessed in the study.

Premedication of intravenous midazolam will be given at the dose of 0.03mg/kg. Remifentanil infusion (Group A – 0.1 mcg/kg/min and Group B – 0.2 mcg/kg/min) will be started after noting the baseline vitals. Hemodynamic changes and analgesic effect of remifentanil during the entire procedure will be observed.

Propofol will be used as induction and maintenance agent and its dose and duration of requirement will be observed. Complications if any will be noted