Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer
- Conditions
- Coronary Artery Disease
- Registration Number
- NCT05366153
- Lead Sponsor
- Baker Heart and Diabetes Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 748
Inclusion Criteria:<br><br>A history of cancer >5 y ago associated with potential cardiotoxicity from chemotherapy<br>and/or radiotherapy (chiefly survivors of breast cancer, Hodgkin's lymphoma and prostate<br>cancer).<br><br>Exclusion Criteria:<br><br> - Unable to provide written informed consent to participate in this study<br><br> - Known coronary artery disease at recruitment<br><br> - History of previous coronary artery disease<br><br> - Inability to acquire interpretable CT images<br><br> - Contraindications/Intolerance to or already taking statin therapy<br><br> - Oncologic (or other) life expectancy <12 months or any other medical condition<br> (including pregnancy) that results in the belief (deemed by the Chief Investigators)<br> that it is not appropriate for the patient to participate in this trial
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of evaluated patients who should undergo CAD prevention
- Secondary Outcome Measures
Name Time Method Proportion with critical CAD;Proportion at intermediate clinical risk;Statin responsiveness