Experimental studies of psychosocial and neural sequelae of childhood interpersonal violence in adults

Not Applicable

Recruiting

Conditions: F43.1
Post-traumatic stress disorder

Registration Number: DRKS00006095

Lead Sponsor: Zentralinstitut für Seelische GesundheitKlinik für Psychosomatik und Psychotherapeutische Medizin

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 140

Inclusion Criteria

Group 1: female; aged between 18 and 65 years; suffering from a posttraumatisstress disorder adter chidhood sexual or physical abuse before the age of 18 (sexual or physical abuse must be the index trauma); at least 3 criteria of a Borderline Personality Disorder (including criterion 6: affective instability).
Group 2: female, aged between 18 and 65 years; childhood sexual or physical abuse before the age of 18.
Group 3: female; aged between 18 and 65 years.

Exclusion Criteria

Group 1: diagnosis of schizophrenia or bipolar I disorder;mental retardation; severe psychopathology which needs to be treated immediately (e.g. BMI < 16); suicide attemt within the last 2 months.
Group 2: diagnoses of Axis-I disorder; diagnosis of Borderline Personality Disorder; any taking of psychotropic drugs.
Group 3: diagnoses of Axis-I disorder; diagnosis of Borderline Personality Disorder; any taking of psychotropic drugs; any traumatic experience; any psychotherapeutic experience

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Experimental investigation:unique investigation of all participants within the frame of the above mentioned study and second investigation for arm 1 (primarily with regards to their tendency to dissociate, intrusive experiences and pain sensitivity). The time frame of the investigations is set until January 2016.<br><br>The time frame of the second investigation of arm 1 starts in July 2016 and is set until July 2017.<br><br>Questionnaires: unique filling in of questionnaires before participating in the experimentalinvestigation as part of the diagnostical interview in the following fields:<br><br>Quality of Life:<br><br>-WHOQOL-BREF ( Skevington et al., 2003)<br>- SF-36 (Ware& Sherbourne, 1992)<br>-EQ-5D (EuroQol-Group, 1987)<br><br>tendency to dissociate:<br>-FDS (Spitzer et al., 2004)

Secondary Outcome Measures

Name	Time	Method
Questionnaires:<br><br>depressive resentment:<br>- BDI-II (Beck et al., 1961))<br><br><br>physical and mental health well-being during the last 7 days:<br>- BSI (Spitzer et al., 2008)