Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children With Cancer
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Childhood Malignant Neoplasm
- Sponsor
- Children's Oncology Group
- Enrollment
- 1200
- Locations
- 184
- Primary Endpoint
- Compliance rate for completion of neuropsychological and behavioral battery
- Status
- Active, Not Recruiting
- Last Updated
- 7 months ago
Overview
Brief Summary
This research trial studies neuropsychological (learning, remembering or thinking) and behavioral outcomes in children and adolescents with cancer by collecting information over time from a series of tests.
Detailed Description
PRIMARY OBJECTIVES: I. To institute procedures to ensure a consistent, streamlined, and efficient administration of the neuropsychological/behavioral tests in a cooperative group setting in order to maximize compliance with a standardized assessment battery conducted at 3 standardized time points. OUTLINE: Parent and child participants complete the COG Standard Neuropsychological and Behavioral Battery at approximately 9, 30, and 60 months post-diagnosis in a 1-2 hour testing session conducted by a neuropsychologist or psychologist. The Battery consists of measures of intelligence, processing speed, attention, memory, language preference, behavioral/social/emotional function, executive function, adaptive function, and quality of life.
Investigators
Eligibility Criteria
Inclusion Criteria
- •The patient must be currently be enrolled or plan to be enrolled on a COG therapeutic study that aims to examine neuropsychological, social, emotional, and/or behavioral functioning
- •The patient must have receptive and expressive language skills in English, French, or Spanish; if a patient meets these criteria but the parent/guardian speaks a language other than English, French, or Spanish, the patient may still be enrolled and tested, and the parent-report measures should be omitted
- •All patients and/or their parents or legal guardians must sign a written informed consent
- •All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met
Exclusion Criteria
- •Patients with a history of moderate to profound intellectual disability (i.e. intelligence quotient \[IQ\] =\< 55) are not eligible for enrollment; PLEASE NOTE: Children with a prior history of attention deficit hyperactivity disorder (ADHD) or a specific learning disability (e.g., dyslexia) are eligible for this study
Outcomes
Primary Outcomes
Compliance rate for completion of neuropsychological and behavioral battery
Time Frame: Up to 72 months post-diagnosis