The effect of vitamin D supplementation compared to placebo on quality of life in stage II-III colorectal cancer patients undergoing adjuvant chemotherapy at Hasan Sadikin Hospital: A single-blind, randomized control trial.
- Conditions
- Colorectal Cancer
- Registration Number
- SLCTR/2024/016
- Lead Sponsor
- Andy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- Not specified
1. Male and female patients diagnosed with colorectal cancer based on the WHO histopathological classification system.
2. All stage II-III colorectal cancer patients undergoing adjuvant chemotherapy at Hasan Sadikin Hospital from May 2024 to April 2025.
3. Patients above 18 years of age.
1. The patient has consumed vitamin D supplements in the last three months.
2. Allergy to vitamin D supplements.
3. The patient has a primary cancer other than colorectal cancer.
4. Patients with short bowel syndrome or patients undergoing gastric bypass surgery.
5. The patient regularly consumes phenobarbital, carbamazepine, dexamethasone, nifedipine, spironolactone, clotrimazole and rifampicin groups.
6. Patient with symptoms of genitourinary stones in the past year.
7. Patient is consuming a thiazide diuretic.
8. Patient with chronic non-infectious disease (liver failure and kidney failure, history of stroke, type I and II diabetes mellitus).
9. Patients with chronic infectious disease (infection lasts >6 months), such as HIV infection, tuberculosis, hepatitis C, HPV, et cetera.
10. Patients who are pregnant, breastfeeding or using oral contraceptives.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of Vitamin D and EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30) score which contains 5 domains (Role, Physical, Cognitive, Emotional, and Social) [3- and 6-months post intervention]<br>
- Secondary Outcome Measures
Name Time Method