MRS AD Study.
Completed
- Conditions
- Alzheimer¡¯s Disease
- Registration Number
- NL-OMON23328
- Lead Sponsor
- Danone Research ¨C Centre for Specialised Nutrition
- Brief Summary
Results published in 'Alzheimer's Research & Therapy', website: https://doi.org/10.1186/s13195-017-0286-2
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Main inclusion criteria:
1. Diagnosis of probable or possible AD with evidence of the pathophysiological process according to the recently revised criteria;
Exclusion Criteria
Main exclusion criteria:
1. Diagnosis of significant neurological and/or psychiatric disease other than AD;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The main 31P-MRS outcome parameters are the total level of Phosphomonoesters (PME), total level of Phosphodiesters (PDE), and the ratio between PME and PDE;<br /><br>2. 1H-MRS outcome parameters: Absolute and relative brain tissue levels of several metabolites.
- Secondary Outcome Measures
Name Time Method Blood parameters: Nutritional blood parameters.