Effect of Carvedilol (drug) in Liver Cirrhosis (Liver Disease)
Not Applicable
- Conditions
- Health Condition 1: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2021/09/036893
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age 18-65 years
Liver cirrhosis
Grade II-III high SAAG ascites
Small low risk or no esophageal varices
CTP 7-12
Exclusion Criteria
Age <18 years
AKI at enrollement (Prior transient volume responsive AKI stage I included)
Post renal or liver transplantation
History of CAD, PVD, ventricular arrythmia, Bronchial asthma
SBP at diagnosis
Severe Hyponatremia (Na <125 MEq/L)
Grade II/III/IV HE
Advanced HCC (BCLC C,D), PVTT, Pregnancy or Lactating mother
High risk varices (Large varices or small high risk varices)
CTP >12
ACLF
Mixed / TB ascites
Bilirubin >5 mg/dl
Known CKD, obstructive uropathy
Patient on MV, NIV, systemic sepsis and shock
Lack of informed consent
Prior intolerance or S/E to carvedilol or diuretics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method