Thoracic epidural or paravertebral analgesia after thoracic surgery
Completed
- Conditions
- Thoracic surgerySurgery
- Registration Number
- ISRCTN55650235
- Lead Sponsor
- Saarland University Medical Center and Saarland University Faculty of Medicine (Germany)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
1. Aged 18 years old and above
2. American Society of Anesthesiologists (ASA) grade I-III
3. Planned thoracic surgery
4. Accepted procedure
Exclusion Criteria
1. Relevant liver or renal disease (Kreatinin > 2 mg/dl, Bilirubin > 2 mg/dl)
2. Inability to communicate
3. Relevant cardiac or neurological disease
4. Chronic treatment with opioids or psychiatric drugs
5. Dependencies
6. Body Mass Index > 30
7. ASA > III
8. Contraindication for a neuraxial procedure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method FV1 measured in L/sec and PEF measured in L/sec- lung function parameters from spirometry (FeV1=expiratory flow after 1 second, PEF=peak expiratory flow, FVC=forced vital capacity). <br><br>The outcome parameters will be measured before the TEA or PVB placement, 15 minutes afterwards and twice daily until day 3 after surgery.
- Secondary Outcome Measures
Name Time Method 1. Pain levels at rest and with coughing (using the verbal numeric rating scale at rest and during coughing) <br>2. Aggregated incidence of nausea, vomiting, pneumonia, atelectases<br>3. Mobilisation (time to stand up, to walk)<br><br>The outcome parameters will be measured before the TEA or PVB placement, 15 minutes afterwards and twice daily until day 3 after surgery.