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临床试验/NCT03597074
NCT03597074已完成不适用

Diagnostic Value of Doppler Ultrasound for Early Prediction of Reversibility of Acute Kidney Injury in Septic ICU Patients

Aristotle University Of Thessaloniki1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2017年3月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
32
试验地点
1
主要终点
RI as a prognostic factor for AKI persistence

研究概览

简要总结

Purpose: The aim of this study was to assess the ability of early discrimination between transient and persistent Acute Kidney Injury (AKI) using the color Doppler Ultrasound derived Renal Resistive Index (RI) and semi-quantitative evaluation of intra-renal vascularization in septic patients in an Intensive Care Unit (ICU).

Methods: Prospective observational cohort study with unselected, with 32 adult consecutive septic patients. Patients were divided into 3 groups: Group 1: patients without progression to AKI, Group 2: transient AKI, Group 3: persistent AKI.

详细描述

Purpose: The aim of this study was to assess the ability of early discrimination between transient and persistent AKI using the color Doppler Ultrasound derived Renal Resistive Index (RI) and semi-quantitative evaluation of intra-renal vascularization in septic patients in an Intensive Care Unit (ICU). Additionally, the investigators aimed to identify whether these indexes are early predictors of the prognosis of renal function in this group of patients. And compare the diagnostic accuracy of those and other renal indexes for the identification of AKI reversibility.

Methods: This was a prospective observational cohort study with unselected, consecutive septic patients included. Thirty-two adult septic patients hospitalized in a general ICU were studied. After the determination of sepsis, patients were divided into 3 groups: Group 1 included patients without progression to AKI, Group 2 included patients with transient AKI and Group 3 patients with persistent AKI.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Septic patients in ICU
  • Age 18 years or older

排除标准

  • ICU stay less than 3 days

结局指标

主要结局

RI as a prognostic factor for AKI persistence

时间窗: 3 days

without units (range 0 to 1)

次要结局

  • semi-quantitative US evaluation of renal vasculature(3 days)
  • FENa (Fractional Excretion of Sodium)(3 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Evangelos Kaimakamis

Principal Investigator

Aristotle University Of Thessaloniki

研究点 (1)

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