To compare injection of drugs (ketamine, levobupivacaine or a combination of both ketamine and levobupivacaine) given under the skin before the surgery for removing uterus in providing pain relief after surgery
Not Applicable
- Conditions
- Health Condition 1: N939- Abnormal uterine and vaginal bleeding, unspecified
- Registration Number
- CTRI/2019/02/017467
- Lead Sponsor
- Vardhman Mahavir Medical College and Safdarjung Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients fulfilling the American society of Anaesthesiologists (ASA) physical status I or II criteria,age from 18years to 75years,Duration of surgery less than 2 hours
Exclusion Criteria
Patients with allergy to study drugs,cardiovascular disease (such as hypertension, tachycardia, arrhythmia, congestive heart failure, and coronary artery disease,Psychiatric disorder,Neurological disease, increased intracranial pressure, seizure disorder, glaucoma, hyperthyroidism
5.Liver or renal dysfunction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cumulative pethidine requirement in 24 hTimepoint: 24 h after surgery
- Secondary Outcome Measures
Name Time Method cumulative pethidine requirement in 1, 2, 6, and 12 h time frameTimepoint: 1, 2, 6, and 12 h after surgery;Occurrence of side effects such as nausea, vomiting, sedation and hallucinationsTimepoint: 0 to 24h;Pain scores at rest and on movement postoperatively at 0, 15 and 30 min and at 1, 2, 6, 12, and 24 hTimepoint: 0, 15 and 30 min and at 1, 2, 6, 12, and 24 h after surgery;Patient satisfaction regarding postoperative analgesia at 24 hTimepoint: 24h after surgery;Time to first pethidine requirementTimepoint: 0 to 24h