Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities
试验速览
- 阶段
- 不适用
- 入组人数
- 160
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to characterize the profile of executive functions and eye movements in several populations of children with developmental disabilities.
详细描述
Abnormal Executive function (EF) profile was considered a major characteristic of Attention deficit / hyperactivity disorder (ADHD) and autism, and is frequently implicated in Developmental coordination disorder (DCD) children as well. The scientific literature implies that the EF profile among these three groups share some common abnormalities, but differ significantly in specific features. Abnormal EF profile may be a core feature of the developmental trajectory of each syndrome.
The fine measurement of eye movements may shed light on the underlying mechanisms of specific disorders, and point to abnormal attention, information processing, or motor organization. Gaze is an important component of social interaction. Eye contact and recognition of other's gaze direction are crucial to empathy assessment.
The current study will embark in the assessment of a wide range of EF in these populations and in a matched control group, as well as their relation to other important parameters such as daily function skills and comorbid neurobehavioral characteristics. It will also assess the pattern of eye movements in response to various visual stimuli in these populations. The main purpose is to characterize the similarities and differences of each of these populations, in terms of EF and eye movements.
Assessment methods:
Clinical parameters:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 4 Years 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age of 4-10 years
- •A medical diagnosis according to the relevant study group
- •Normal vision without glasses or contact lens.
- •Exclusion Criteria - clinical groups:
- •Intelligence Quotient below 70
- •A known brain damage
- •A known hearing impairment
- •Regular use of medications (except for psychostimulants)
- •Evidence for a known genetic syndrome
- •History of fetal CMV infection, birth asphyxia, major head injury or epilepsy
- •Exclusion Criteria - control group:
- •Intelligence Quotient below 70
- •Regular use of medications
- •Evidence for a neurological / psychiatric disorder, birth injury, developmental delay, head injury, or other medical disorders that affect the central nervous system
- •Family History - first degree) of autism, DCD, ADHD or other neurological/psychiatric disorder
排除标准
- 未提供