JPRN-jRCTs061180081进行中（未招募）2 期
Preoperative chemoradiothrepy for lower advanced rectal cancer patients using TS-1+Oxaliplatin+Bevacizumab regimen (phase 2 study).
Shimada Mitsuo0 个研究点目标入组 47 人开始时间: 2019年3月20日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 47
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 80age old（—）
- 性别
- All
入选标准
- •Patients satisfied fully with below criteria
- •1) Diagnosed as adenocarcinoma
- •2) cT2~T4 and cN0~N3, resectable case
- •3) Tumor location (including Rb region)
- •4) Measurable tumor
- •5) No peritoneal dissemination
- •6) No distant metastasis
- •7) 20~80 years old
- •8) Performance status 0~2
- •9) Patinets with normal organ function
- •10) No pre treatment
- •11) Patientss with informed consent
- •12) Patients able to take foods orally
排除标准
- •1) Interstitial pneumonia
- •2) Much ascites or pleural effusion
- •3) Double cancer or treated cancer less than 5 years disease free survival
- •4) Strong stenosis(fiber cannot pass through)
- •5) Peritoneal dissemination
- •6) Infection,Ileus
- •7) Severe diarrhea
- •8) Severe diabete mellitus
- •9) Severe hyper tension
- •10)Heart failure,liver failure,renal failure
- •11) Past history of thrombosis
- •12) Intraabdominal inflammation
- •13) Severe paresthesia or perceived failure
- •14) Brain metastasis
- •15) Congenital hemorrhagic disorder or blood coagulation disorder
- •16) Psychiatric disorder
- •17) Pregnant woman or patients hoping of pregnancy
- •18) Past history of severe drug allergy
- •19) Contraindication of each trial drugs
- •20) Past history of drug allergy for each trial drugs
- •21) Continuous steroids administration
- •22) Patients with anti-coagulant drugs
- •23) Patients ncompatible with this trial judged by medical staff
研究者
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