Quantitative Evaluation of the Progression of Liver Disease, Using ShearWaveTM

• Conditions: Liver Disease; Heart Failure

• Registration Number: NCT02070315
• Lead Sponsor: Baylor Research Institute

Brief Summary

Liver biopsy for the assessment of fibrosis has multiple limitations. Liver ShearWaveTM Elastography may provide a non-invasive, fast, and reproducible alternative for the quantitative assessment of liver fibrosis.

Detailed Description

To obtain a quantitative evaluation of the progression of liver disease, using ShearWaveTM Elastography measurements obtained with the Supersonic Imagine Aixplorer ultrasound machine.

To compare the glomerular filtration rate and the quantitative evaluation of the progression of renal disease, using ShearWaveTM Elastography measurements obtained with the Supersonic Imagine Aixplorer ultrasound machine in post-liver transplantation patients.

Study Timeline

• Study Start: 2012-02
• Study First Submitted: 2013-01-08
• Study First Submitted QC: 2014-02-21
• Study First Posted: 2014-02-25
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-20
• Last Update Posted: 2020-02-21
• Primary Completion: 2020-11
• Study Completion: 2020-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Males and Females over the age of 18
• Patients of Liver Consultant's of Texas Dallas office, with chronic liver disease or liver transplant patient seen in Liver Transplant Clinic
• Patients diagnosed with heart failure

Exclusion Criteria

• Any person unable to provide an informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Shearwave Elastography Ultrasound	1 day	Patients will have a scan performed at their regularly scheduled clinic visits.

Trial Locations

Locations (1)

Baylor University Medical Center; 🇺🇸 Dallas, Texas, United States