A pilot study to examine the effect of vitamin C on bone turnover and antioxidant levels in postmenopausal women with low bone density.
Completed
- Conditions
- Musculoskeletal Diseases: OsteoporosisMusculoskeletal DiseasesOsteoporosis without pathological fracture
- Registration Number
- ISRCTN44380631
- Lead Sponsor
- Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 0
Inclusion Criteria
Postmenopausal women with low bone density. Consenting healthy postmenopausel women with low bone density; osteopenia (Tscore<-1.0) as defined by the WHO 1994.
Exclusion Criteria
On treatment for osteroporosis or taking any bone active drugs (e.g. oestrogens, steroids, vitamin D) or known to be suffering from diseases which can affect the skeleton such as renal or liver failure, malabsorption, thyrotoxicosis).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link vitamin C to bone turnover modulation in postmenopausal osteoporosis?
How does vitamin C supplementation compare to bisphosphonates in managing low bone density in postmenopausal women?
Are there specific biomarkers that predict postmenopausal women's response to vitamin C in improving bone density and antioxidant levels?
What are the potential adverse events associated with high-dose vitamin C in postmenopausal women with osteoporosis?
What combination therapies involving vitamin C show promise in enhancing antioxidant levels and bone density in osteoporosis patients?