A pilot study to examine the effect of vitamin C on bone turnover and antioxidant levels in postmenopausal women with low bone density - Vitamin C study
- Conditions
- low bone density / osteoporosispostmenopausal women
- Registration Number
- EUCTR2004-002975-17-GB
- Lead Sponsor
- Epsom & St Helier University Hospitals NHS Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
Post menopausal women
Low bone density (T score < -1.0)
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Taking drugs that affect bone metabolism
Taking vitamin C supplements within the last 4 weeks
Suffering from diseases (eg renal failure, rheumatoid arthritis) that can adversely affect bone density and bone metabolism
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: We want to see if vitamin C (a natural antioxidant) reduces bone turnover in women with postmenopausal osteoporosis.<br>;Secondary Objective: ;Primary end point(s): Changes in biochemical markers and antioxidant levels from baseline to end of study in vitamin C group group compared to controls
- Secondary Outcome Measures
Name Time Method